Dengwen Li Selected Research

Familial cylindromatosis

8/2010	Tumour suppressor CYLD is a negative regulator of the mitotic kinase Aurora-B.
4/2008	The tumor suppressor CYLD regulates microtubule dynamics and plays a role in cell migration.

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Dengwen Li Research Topics

Disease

16	Neoplasms (Cancer) 01/2021 - 03/2008
10	Breast Neoplasms (Breast Cancer) 01/2020 - 05/2009
8	Pancreatic Neoplasms (Pancreatic Cancer) 01/2019 - 06/2010
5	Neoplasm Metastasis (Metastasis) 01/2020 - 01/2014
4	Carcinogenesis 01/2019 - 03/2008
4	Inflammation (Inflammations) 01/2018 - 01/2014
2	Neurodegenerative Diseases (Neurodegenerative Disease) 04/2021 - 04/2011
2	Pathologic Processes 01/2021 - 02/2016
2	Adenomatous Polyposis Coli (Familial Adenomatous Polyposis) 01/2016 - 05/2008
2	Parkinson Disease (Parkinson's Disease) 04/2011 - 05/2009
2	Familial cylindromatosis 08/2010 - 04/2008
1	Infections 01/2022
1	Hematologic Neoplasms (Hematological Malignancy) 01/2020
1	Multiple Myeloma 01/2020
1	Non-Hodgkin Lymphoma (Lymphosarcoma) 01/2020
1	Anemia 11/2019
1	Lung Neoplasms (Lung Cancer) 11/2017
1	Lymphatic Metastasis 02/2016
1	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 01/2015
1	Cough 01/2015
1	Ciliopathies 11/2014
1	Wounds and Injuries (Trauma) 04/2014
1	Cardiovascular Diseases (Cardiovascular Disease) 04/2014
1	Neuroblastoma 01/2014
1	Parkinsonian Disorders (Parkinsonism) 04/2013
1	Leukemia 01/2013
1	Hypoxia (Hypoxemia) 06/2007

Drug/Important Bio-Agent (IBA)

16	Proteins (Proteins, Gene)FDA Link 01/2019 - 04/2008
6	Deubiquitinating EnzymesIBA 01/2021 - 05/2010
6	Carrier Proteins (Binding Protein)IBA 01/2019 - 04/2008
5	Histone Deacetylase 6IBA 01/2020 - 11/2013
5	Messenger RNA (mRNA)IBA 11/2017 - 11/2013
5	Pharmaceutical PreparationsIBA 06/2017 - 05/2009
5	cytoplasmic linker protein 170 (restin)IBA 04/2014 - 03/2012
4	Paclitaxel (Taxol)FDA LinkGeneric 06/2017 - 05/2009
3	TubulinIBA 01/2022 - 01/2014
3	Biomarkers (Surrogate Marker)IBA 01/2019 - 01/2014
3	Phosphotransferases (Kinase)IBA 11/2017 - 06/2007
3	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 04/2013 - 05/2009
2	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA 01/2020 - 01/2014
2	MAP Kinase Kinase Kinase 5IBA 11/2017 - 11/2016
2	Glycine (Aminoacetic Acid)FDA LinkGeneric 08/2010 - 04/2008
1	Cytoskeletal ProteinsIBA 04/2021
1	Indicators and Reagents (Reagents)IBA 01/2019
1	MonosaccharidesIBA 01/2018
1	Threonine (L-Threonine)FDA Link 11/2017
1	Calcium-Binding ProteinsIBA 01/2017
1	CytokinesIBA 01/2017
1	Interleukin-17 (Interleukin 17)IBA 01/2017
1	TNF Receptor-Associated Factor 6 (TRAF6)IBA 03/2016
1	Lysine (L-Lysine)FDA Link 03/2016
1	UbiquitinIBA 03/2016
1	TNF Receptor-Associated Factor 2 (TRAF2)IBA 03/2016
1	Centrosomal Associated ProteinsIBA 02/2016
1	CarbohydratesIBA 02/2016
1	AntigensIBA 02/2016
1	pericentrinIBA 02/2016
1	AgarIBA 02/2016
1	KinesinsIBA 01/2016
1	Tumor Suppressor Proteins (Proteins, Tumor Suppressor)IBA 01/2015
1	Noscapine (Narcotine)IBA 01/2015
1	tubacinIBA 01/2014
1	Rho Guanine Nucleotide Exchange FactorsIBA 01/2013
1	Polo-Like Kinase 1IBA 10/2012
1	Gemcitabine FDA Link 10/2012
1	Farnesyltranstransferase (Farnesyltransferase)IBA 05/2012
1	Caspase 3 (Caspase-3)IBA 03/2012
1	Proteasome Endopeptidase Complex (Proteasome)IBA 04/2011
1	Adenosine Triphosphatases (ATPase)IBA 06/2010
1	Dynactin ComplexIBA 05/2008
1	Vinca AlkaloidsIBA 03/2008
1	Aurora KinasesIBA 03/2008
1	CREB-Binding ProteinIBA 06/2007
1	Histone Deacetylases (Histone Deacetylase)IBA 06/2007
1	Transcription Factor AP-1 (Transcription Factor AP 1)IBA 06/2007
1	Hypoxia-Inducible Factor 1IBA 06/2007

Therapy/Procedure

6	Therapeutics 01/2020 - 06/2010
4	Drug Therapy (Chemotherapy) 11/2019 - 03/2008